Exam Practice Test 1 - 50 Questions (answers with explanation)
The 50 questions in this test are randomized each time you start, ensuring a different order every time
1. A 34-year-old female presents with symptoms of fatigue, weight gain, increased sensitivity to cold, worsened mood and constipation. Current lab work reveals a hemoglobin of 14.2 g/dL, creatinine of 1.1 mg/dL, B12 of 400 pg/mL, folic acid of 15 ng/mL, and TSH of 26.5 mIU/L. Current medications include: Synthroid 50 mcg daily, Zoloft (sertraline) 75 mg daily, and folic acid 1 mg daily. The patient is taking all medications as directed. What is the most appropriate course of action?
A. Increase Zoloft to 100 mg daily
B. Consider the addition of vitamin B12
C. Increase Synthroid to 75 mcg daily
D. None of the above
Answer: Only for registered users. Please login!
2. How many mg of a medication will it take to create a 1,500 mL product at a concentration of 1:10,000?
Fill in the Blank:
Answer: Only for registered users. Please login!
3. Which of the following would be most appropriate in a patient with HIV requiring PCP (Pneumocystis carinii pneumonia) prophylaxis?
A. Doxycycline
B. Bactrim
C. Erythromycin
D. Augmentin
Answer: Only for registered users. Please login!
4. Which of the following medications for diabetes would carry the least risk of hypoglycemia?
A. Glucophage
B. Glucotrol
C. Lantus
D. Humalog
Answer: Only for registered users. Please login!
5. A physician writes for a dose of Tylenol 20 grains twice daily. What dose of acetaminophen is this?
A. 325 mg twice daily
B. 650 mg twice daily
C. 1000 mg twice daily
D. 1300 mg twice daily
Answer: Only for registered users. Please login!
Answer the following 3 questions based on the case:
A 48-year-old male has a history of bipolar disorder, Crohn’s disease, and was diagnosed with atrial
fibrillation within the last year. He was prescribed amiodarone for atrial fibrillation. Other medications
include Depakote, Lamictal, aspirin, and azathioprine.
Vital signs include:
● Pulse = 76 bpm
● Blood pressure = 135/68 mmHg
● Respirations = 18 breaths per minute
● Weight = 168 lbs
Current laboratory testing reveals:
● Creatinine = 1.1 mg/dL
● Potassium = 4.3 mEq/L
● Sodium = 139 mEq/L
● Albumin = 4.1 g/dL
● AST = 798 U/L
● ALT = 924 U/L
● Hemoglobin = 14.1 g/dL
● CPK = 86 units/L
6. Which medications could contribute to the lab abnormalities? Select all that apply.
A. Depakote
B. Aspirin
C. Azathioprine
D. Amiodarone
Answer: Only for registered users. Please login!
7. Based upon the medication list, which of the following is a significant interaction?
A. Depakote/Lamictal
B. Amiodarone/Aspirin
C. Azathioprine/Aspirin
D. Depakote/Azathioprine
Answer: Only for registered users. Please login!
8. The patient above has also had an issue with multiple infections. Which medication puts them at the highest risk for recurrent infections?
A. Lamictal
B. Amiodarone
C. Depakote
D. Azathioprine
Answer: Only for registered users. Please login!
9. In a patient with a creatinine clearance of less than 30 mL/min and ongoing edema that is not helped by increasing the furosemide dose, which of the following would be the best option to help with edema?
A. Adding hydrochlorothiazide
B. Adding Bumex
C. Adding metolazone
D. Adding captopril
Answer: Only for registered users. Please login!
10. Which of the following hypertension medications can also be beneficial for BPH symptoms?
A. Norvasc
B. Hytrin
C. Zestril
D. Lasix
Answer: Only for registered users. Please login!
11. Which of the following is not a common physiological complication in the aging of an elderly patient? Select all that apply.
A. Skin thickening, increasing the risk of skin and soft tissue infections
B. Slowed GI tract and possible reduced absorption of some vitamins and minerals like B12 and iron
C. A drop in GFR which can contribute to the accumulation of many medications
D. Increased concentration of albumin due to loss of intravascular fluid/dehydration
E. Loss of muscle mass, reduced physical conditioning
Answer: Only for registered users. Please login!
Answer the following three questions based on the information:
A patient has been given a 500 mL bag that contains 60 mEq of potassium chloride. The IV is delivering 20
drops per mL at a rate of 8 drops per minute. It has been running for about 3 hours.
The molecular weight of K+ =39 g/mol and Cl- =35.5 g/mol.
12. How many mEq of potassium has this patient been given?
Fill in the blank to the nearest hundredth decimal place:
Answer: Only for registered users. Please login!
13. How many mg of potassium chloride has this patient been given?
Fill in the blank to the nearest whole number:
Answer: Only for registered users. Please login!
14. Which of the following medications would be likely to contribute to hyperkalemia, especially in patients already receiving an ACE inhibitor or an ARB? Select all that apply.
A. Spironolactone
B. Trimethoprim
C. Lasix
D. Zaroxolyn
Answer: Only for registered users. Please login!
15. Which of the following correctly ranks the strength of evidence from highest to lowest in drug study designs?
A. Case study, Case controlled series, Cohort study, Randomized controlled clinical trial
B. Randomized controlled clinical trial, Cohort study, Case controlled series, Case study
C. Cohort study, Randomized controlled clinical trial, Case study, Case controlled series
D. Case controlled series, Cohort study, Randomized controlled clinical trial, Case study
Answer: Only for registered users. Please login!
16. An 85-year-old female is on metoprolol for atrial fibrillation, Bactrim for UTI prophylaxis, and felodipine for hypertension. This patient had a recent cerebrovascular accident (CVA) and the primary provider would like to start Coumadin on this patient. Which of the following would be the most appropriate starting dose?
A. 2.5 mg daily
B. 5 mg daily
C. 2.5 mg twice daily
D. 10 mg daily
Answer: Only for registered users. Please login!
17. Which of the following medications is least likely to cause renal failure?
A. Augmentin
B. Gentamicin
C. Losartan
D. Celebrex
Answer: Only for registered users. Please login!
18. What is the most common cause of erythropoietin failure?
A. B12 deficiency
B. Iron deficiency
C. Poor absorption in cachectic patients
D. Liver disease
Answer: Only for registered users. Please login!
19. A 55-year-old male with a history of alcoholism is diagnosed with liver failure. Current laboratory testing reveals elevated ammonia levels. What is the most appropriate therapy to treat the elevated ammonia level?
A. Propranolol
B. Metoclopramide
C. Lactulose
D. Thiamine
Answer: Only for registered users. Please login!
20. What is the active metabolite of codeine?
A. Fentanyl
B. Oxycodone
C. Morphine
D. Methadone
Answer: Only for registered users. Please login!
21. What is the primary mechanism of action of Requip?
A. Inhibits NMDA receptors
B. Inhibition of GABA receptors
C. Dopamine agonist
D. Activate Mu receptors
Answer: Only for registered users. Please login!
22. Which of the following side effects would be least likely with Aricept?
A. Nausea
B. Constipation
C. Weight loss
D. Cognitive changes
Answer: Only for registered users. Please login!
23. A 62-year-old Caucasian male presents to the hospital with NSTEMI. He became short of breath prior to being admitted to the hospital. Biomarkers for troponin and creatine kinase (CK) were noted to be elevated upon lab assessment.
His labs are as follows:
● Creatinine clearance: 71 mL/min
● Sodium: 138 mEq/L
● Potassium: 3.4 mEq/L
● LFTs: within normal range
● Hemoglobin: 14.1 g/dL
● Platelets: 297,000 per uL
● TIMI Risk score: 4
● BP: 152/92 mmHg
● Pulse: 79 bpm
Which of the following agents would be recommended upon discharge for this patient?
Select all that apply.
A. Atorvastatin
B. Aspirin
C. Metoprolol
D. Lisinopril
E. Isosorbide mononitrate
Answer: Only for registered users. Please login!
Answer the following question based on the information presented.
A patient whose weight is 145 lbs and whose height is 5’3” is to receive a dose of Drug X. The dosing for Drug X is 1200 mg/m2.
24. What dose (in mg) would be required for this patient?Round to the nearest hundred.
Fill in the blank:
Answer: Only for registered users. Please login!
Answer the following question based on the information presented.
A patient whose weight is 145 lbs and whose height is 5’3” is to receive a dose of Drug X. The dosing for Drug X is 1200 mg/m2.
25. What is this patient’s BMI? Round to the nearest tenth decimal place.
Fill in the blank:
Answer: Only for registered users. Please login!
26. A 78-year-old female presented to the emergency department with increased coughing, shortness of breath, and a mild elevation in temperature. The patient has type 2 diabetes. She is diagnosed with community-acquired pneumonia and the decision for outpatient antibiotic therapy is made. What is the most appropriate empiric therapy?
A. Azithromycin
B. Ciprofloxacin
C. Doxycycline
D. Amoxicillin-clavulanate plus doxycycline
Answer: Only for registered users. Please login!
27. A 55-year-old male with a past medical history of GERD, hypertension, and alcoholism is diagnosed with a
C. difficile infection. This is the first known episode. Which is the most appropriate therapy?
A. Metronidazole
B. Oral vancomycin
C. Clindamycin
D. Doxycycline
Answer: Only for registered users. Please login!
28. A 74-year-old female is currently taking the following medications: famotidine, diltiazem, amiodarone, and Tylenol. She has been experiencing edema of late. Which medication would be most likely to cause or worsen this symptom?
A. Famotidine
B. Diltiazem
C. Amiodarone
D. Tylenol
Answer: Only for registered users. Please login!
29. A 32-year-old female presents to the pharmacy with a bottle of St. John’s wort. She is currently on birth control containing estrogen. What is the concern with taking these together?
A. St. John’s wort is an enzyme inhibitor and can reduce estrogen concentrations in the body
B. St. John’s wort is an enzyme inducer and can reduce estrogen concentrations in the body
C. St. John’s wort is an enzyme inhibitor and can increase estrogen concentrations in the body leading to increased risk of adverse effects
D. St. John’s wort is an enzyme inducer and can increase estrogen concentrations in the body leading to increased risk of adverse effects
Answer: Only for registered users. Please login!
30. Which of the following medication patches would it be appropriate to cut and still use?
A. Fentanyl
B. Exelon
C. Lidoderm
D. Scopolamine
Answer: Only for registered users. Please login!
31. Which antidepressant would be most beneficial in a patient who is trying to avoid the side effect of sexual dysfunction?
A. Zoloft
B. Lexapro
C. Wellbutrin
D. Pamelor
Answer: Only for registered users. Please login!
32. Which of the following medications can increase the risk for osteoporosis?
A. Zofran
B. Prednisone
C. Tramadol
D. Methotrexate
Answer: Only for registered users. Please login!
33. The prescription for eye drops calls for 2 drops in the left eye twice daily. Given the following choices of package size, how many milliliters should be dispensed to get at least a month’s supply while minimizing excess?
A. 2.5 mL
B. 5 mL
C. 7.5 mL
D. 10 mL
Answer: Only for registered users. Please login!
34. A 33-year-old male with a history of asthma was recently started on an albuterol inhaler. Which of the following would be an important education point?
A. Rinse mouth with water and and spit following administration to prevent thrush
B. This medication may interact with over the counter antitussives, like Robitussin
C. This medication may cause an short-term increase in heart rate
D. This medication should not be used in patients with a history GERD
Answer: Only for registered users. Please login!
35. Which of the following medications would be most useful in the treatment of hyperphosphatemia in chronic kidney disease?
A. Carafate
B. Sevelamer
C. Calcitriol
D. Miacalcin
Answer: Only for registered users. Please login!
36. Which of the following would be appropriate monitoring for adverse effects of hydroxychloroquine?
A. Routine foot exams
B. Routine eye exams
C. CPK (especially with statin therapy)
D. Neuropathy
Answer: Only for registered users. Please login!
37. Which of the following would be least appropriate for the management of acute pain?
A. Ibuprofen
B. Duragesic
C. Oxycodone
D. Tramadol
Answer: Only for registered users. Please login!
38. A 78-year-old male has a history of diabetic neuropathy and BPH. He presents with symptoms of worsening neuropathy. He has been treating it with over the counter Tylenol. Which medication would be least appropriate to initiate?
A. Duloxetine
B. Amitriptyline
C. Pregabalin
D. Neurontin
Answer: Only for registered users. Please login!
39. Which of the following medications is most likely to cause a GI bleed?
A. Celebrex
B. Ketorolac
C. Acetaminophen
D. Ultram
Answer: Only for registered users. Please login!
40. Capsaicin is a topical product used in the treatment of muscle pain. What is its primary mechanism of action?
A. Acts as a counter irritant at site of application
B. Depletes substance P
C. Increases protein C at the site of action
D. Inhibition of prostaglandin synthesis
Answer: Only for registered users. Please login!
41. A 77-year-old male with a history of multiple DVTs is currently receiving warfarin therapy. He is diagnosed with osteomyelitis and treatment with rifampin is initiated. What will likely happen to INR when rifampin is discontinued?
A. INR will go up
B. INR will go down
C. INR will be unaffected
D. Too little information to tell
Answer: Only for registered users. Please login!
42. A 57-year-old male has been initiated on Aldactone. What should be monitored?
A. Liver function
B. Potassium levels
C. Albumin
D. Pulses
Answer: Only for registered users. Please login!
43. What is the primary objective of HIPAA?
A. Facilitate communication amongst healthcare professionals
B. Protect the patient’s right to keep their healthcare information private
C. Minimize risk of frivolous lawsuits against medical professionals
D. Improve cost containment measures with pharmaceutical manufacturers
Answer: Only for registered users. Please login!
44. A patient that is a poor CYP3A4 metabolizer would have what effect on the use of Plavix?
A. Increased risk of bleed
B. Increased risk of clot
C. No change
D. Increased risk at low doses and lower risk at higher doses
Answer: Only for registered users. Please login!
45. What class of medication would likely be used for esophageal varices associated with liver cirrhosis?
A. ACE inhibitor
B. Alpha blocker
C. Calcium channel blocker
D. Beta-blocker
Answer: Only for registered users. Please login!
46. Which of the following medications warrants monitoring for pulmonary fibrosis?
A. Amiodarone
B. Hydralazine
C. Nabumetone
D. Imodium
Answer: Only for registered users. Please login!
47. A 66-year-old female was recently started on Lamictal. What is an important educational point that this patient should look out for?
A. The medication can cause discoloration of the urine
B. Immediately report any sign of rash to provider
C. The medication should not be taken with Tylenol
D. The medication can cause muscle soreness
Answer: Only for registered users. Please login!
48. What is the antidote to heparin?
A. Methylene blue
B. Phytonadione
C. Protein C
D. Protamine sulfate
Answer: Only for registered users. Please login!
49. Which of the following medications works by antagonizing muscarinic receptors in the bladder?
A. Ditropan
B. Phenazopyridine
C. Myrbetriq
D. Flomax
Answer: Only for registered users. Please login!
Answer the following question based on the information below:
A 78-year-old white male with a history of atrial fibrillation, hypertension, GERD, and CHF is currently
receiving metoprolol 25 mg twice daily, digoxin 0.25 mg daily, omeprazole 20 mg daily, Pepcid 40 mg at
bedtime, and aspirin 81 mg daily.
Recent labs reveal an elevation in creatinine of 1.8 mg/dL. 6 months ago, creatinine was 1.1 mg/dL.
Other information:
● Height = 6 feet 2 inches
● Weight 178 lbs
● Blood pressure = 128/78 mmHg
● Pulse = 62 bpm
● Respiration rate = 21 breaths per minute
50. Which medication is this change in creatinine most likely to require dose adjustments?
A. Metoprolol
B. Pepcid
C. Omeprazole
D. Aspirin
Answer: Only for registered users. Please login!
